As large enterprises continually strengthen security around their system and data assets, we're seeing adoption of products like CyberArk's Enterprise Password Vault (https://www.cyberark.com/products/privileged-account-security-solution/enterprise-password-vault/ )
The system is essentially a central repository that secures and automatically rotates passwords for privileged accounts- things like a functional account you would use to run workflows against a certain database or set of systems.
It would be great if Alteryx could build both Server (Run As Account) and Designer (for individual database connections) integrations with a tool like that.