When I first started using Alteryx I did not use macros or the Runtime Tab much at all and now I use both a lot but...I can't use them together.
When working in a macro there is no Runtime Tab. While working on a macro and testing it you can't take advantage of any of the handy features in the Runtime Tab. I am assuming a macro will inherit any settings from the Flow that calls it, can't find anything in the community or "help" to confirm that though, but this is not helpful while developing and testing.