As recommended by HenrietteH at Alteryx to submit as a suggested future enhancement.
I have Oracle 11 and Oracle 12 clients on my machine. With Toad, I can toggle between either client's current home, but it appears that is not a feature in Alteryx. So now I am unable to execute ETL jobs off my machine or server because Alteryx gets confused. Currently, the only remedy I can think of is having 11 client uninstalled, which can cause dependency issues if I need it in the future.