There's lots of options. You could look at creating workflow constants: https://community.alteryx.com/t5/Alteryx-Designer-Desktop-Discussions/Using-a-Constant-in-the-Input-...
This would mean you update all the paths in a really quick fashion.
There's also workflow dependencies:
https://help.alteryx.com/current/en/designer/workflows/workflow-dependencies.html#idm45439313921616
They can make things really easy for overwriting file input paths.
Have a look at those two, see what you think. The options aren't limited to just those though!
All the best,
BS
You can also consider making the paths relative to a SharePoint site or a OneDrive site so that when you transfer over a workflow, your colleagues will have the same input and output sources.
@BS_THE_ANALYST Has some good points and resources - have a go at them!