I am receiving this error "the exception unknown software exception(0xe06d7363) occured in the application at location 0x00007FF98EC649B9" whenever I run my Alteryx workflow. In the results window the error reads "the designer reported you have a bug. the pipe has been ended". I have tried turning off the AMP engine and running it but the error is still showing up. I have also tried reducing the data type sizes.
Since you already tried to run without AMP, maybe this is related to the anti-virus. See this video https://www.youtube.com/watch?v=04ku926pTm0