With the release of 10.6 came awesome new features, and an upgrade in the underlying R version (from 3.1.3 code named "Smooth Sidewalk," to 3.2.3 code named "Wooden Christmas-Tree"). Using the incompatible R version will cause errors in your R macros.
Simply make sure that your Predictive Tools download is the version compatible with your Alteryx Designer version:
Users on 10.5 should continue to use the R3.1.3 version.
When using Alteryx and Microsoft Revolution R Enterprise, a separate predictive tools install is required (in green). For details, see the Alteryx and Revolution Analytics Integration Guide.
And remember to use the non-Admin Predictive version with non-Admin versions of Alteryx Designer.
To install Predictive Tools for Alteryx 10.0, go to Previous Releases. For Alteryx 9.5, within Designer, go to Help > Install Predictive Tools.
Happy Alteryx-ing!
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