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You cannot use the same multi-row function on multiple columns, however, you can transpose your columns so that they are in 2 columns (Name and Value) and then use the multi-row function grouped by Name. You would need to use the cross tab tool after the calculation to get your data structure back to the original. I would demonstrate but I'm not sure what fields this would be appropriate for.
You could also use a multi-row formula for each calculation.