It would be nice if AWS Glue had first class support in Alteryx. This would allow Alteryx to more seamlessly connect to data sources defined in the Glue metastore catalog. That alone would be handy and save on extra book-keeping. AWS Glue also has an ETL language for executing workflows on a managed Spark cluster, paying only for use. Integrating this big data tool with Alteyrx would be interesting as a way to execute in-database Spark workflows without the extra overhead of cluster management or Alteyrx connectivity
https://aws.amazon.com/glue/configuration.